Where is hyaluronic acid located? Hyaluronic acid for the face: effect, price, contraindications, indications, pros, cons. Importance of acid for skin

Hyaluronic acid or hyaluronate is found in nervous tissue, epithelial tissue and connective tissue. It is the main component of the extracellular matrix. Biological fluids containing it are saliva, synovial fluid and others. The enormous influence of hyaluronic acid on proliferation and cell migration makes it a component of many modern “elixirs of youth.”

Why is hyaluronic acid needed?

The body of an average-weight adult contains about 15 g of hyaluronic acid, which undergoes a process of synthesis and breakdown every day. It is considered one of the main components of biological lubricants (like lubricin). Being the main component of synovial fluid, this acid is responsible for the level of viscosity of this fluid.

Hyaluronate refers to the substances that make up articular cartilage, where this acid is present as an essential membrane of each cell. Thanks to its presence, negative charge aggregates are formed on the cartilage, which process water, which increases the cartilage’s resistance to compression. Containing hyaluronic acid cells in the skin regenerate quickly and regularly. It is the synthesis of this acid in the cells of the dermis that ensures the elasticity of the skin.

In other words, hyaluronic acid is an important component that is responsible for the elasticity of cartilage, tissue hydrodynamics, and interaction with cellular receptors. It is effectively used in the following areas:

  • In the treatment of tissue diseases such as osteoarthritis, cataracts, etc.
  • In cosmetic surgery as injections to fill age wrinkles.
  • As a component of preparations intended for soft tissue enlargement.
  • As the basis of many anti-cancer drugs.
  • In cosmetology, it is used not only as subcutaneous injections that prolong the youth of the face, but also as a component of creams, lotions, and decorative cosmetics.

Functionality of hyaluronate


Hyaluronic acid attracts 1000 times its own weight in water. This feature has made it a powerful cell moisturizer. It prolongs their health, functionality and elasticity. This substance is found in the most important organs of the human body. It is found in joints, skin, eyes, and heart valves. The main function of hyaluronate is to bind water in the intercellular free space, which helps to increase resistance before a process such as compression.

Even one molecule of this acid is capable of holding 500 molecules of water around itself, which makes it a powerful source of intracellular hydration and nutrition. This is of great importance in prolonging the youth of tissues. And its ability to provide protective natural lubrication at the location is necessary for visual acuity, joint mobility, and normalization of intraocular pressure.

Due to the functions it performs, hyaluronic acid is intensively used in the fight against aging. Knowing which products contain this substance, you can provide your body with the necessary amount for every day.

Signs of a lack of hyaluronic acid in the body are the appearance of early wrinkles (“crow’s feet”, forehead wrinkles), dry skin, the formation of nasolabial folds, loss of skin elasticity and “crunch” in the joints. In its consistency, this substance resembles a cluster of gel-like molecules with a water base. Great importance A hormone such as estrogen plays a role in the production of hyaluronate. It is believed that this acid is found in excess in children and women aged 18 to 26 years. To the rest age categories The presence of hyaluronic acid in the body should be corrected by consuming foods that contain this substance in large quantities.

Understanding which foods contain a lot of hyaluronic acid will help you adjust your diet correctly. This will allow you to replenish the reserves of this substance, important for the health and youth of the body, naturally and without the use of medications.

Hyaluronic acid for skin

The popularity of using preparations containing hyaluronic acid is ensured by the fact that the substance has the ability to normalize the water balance of the skin and qualitatively fills even deep wrinkles. Since the fight against wrinkles may be necessary not only for those with mature skin, but also for those who have just begun to notice signs of aging, there are cosmetic products with different molecular textures. To combat early wrinkles, it is enough to use creams and serums of low molecular structure. Such products help form a special film on the skin that does not allow air to pass through. This film moisturizes the skin and retains fluid in the cells.

As for products based on hyaluronic acid, which have a high molecular structure, they are effective even against very deep wrinkles. Such compositions have a powerful effect from within the skin, at its cellular level. They not only retain moisture in the epidermis, but also enhance the production of collagen and elastin. The intense increase in these proteins is ensured precisely by the fact that in the data cosmetics contains high molecular weight hyaluronic acid.

Cosmetologists often call this acid a hyaluronic “sponge”. This is explained by the fact that even a 1% solution of the substance has a significant viscosity, and a 2% solution, which contains 98% water, can be picked up and rolled into a ball, like a gel-like mass. This is a property of molecules of this substance, and the fact that half of all acid is concentrated in the epidermis is used with great success in modern products in the fight against age-related skin changes.

You can provide your skin with elasticity and high-quality hydration by consuming foods that contain hyaluronate. It should be remembered that in processes with this acid, vitamins P and C actively interact, the balance of which should also be taken care of.

What products contain hyaluronic acid

Hyaluronic acid is often found in foods. You need to know which product categories contain this substance in large quantities. Understanding what exactly needs to be consumed regularly, you can successfully subject the family diet to the necessary adjustments. The systematic nature of such nutrition will provide the body with a strong advantage over old age, diseases of the joints, eyes, etc.

What main products contain hyaluronic acid:

  1. Animal sources.
  2. Soy products.
  3. Red natural wines.
  4. Fruit.

Hyaluronic acid can be found in the combs of roosters and chickens, as well as in a decoction of chicken feet. Rich meat broths prepared using not only meat, but also bones, skin and tendons as raw materials are especially rich in this substance. Traditional chicken broth or jellied turkey and pork are rich in hyaluronic acid and are recommended for food as a source of this substance. It is animal food that is the main supplier of hyaluronate.

As for soy products, this is an ideal option for those who do not like rich broths or consider themselves vegetarians. For example, a large number of hyaluronic acid is found in soybeans. This product of plant origin contains phyto-estrogens necessary for the production of hyaluronic acid. Those who prefer plant-based foods to meat should also remember about soy products such as tofu and soy milk. Their consumption increases the synthesis of this acid in the human body.

You should also know in which drinks you can find the source of the catalysts necessary for the production of this acid. These are predominantly red grape wines made according to traditional recipes. Naturally, when talking about wine, we should mean only natural drinks prepared by processing grapes along with seeds and skins. By drinking one or two glasses of this red wine a day, you can provide your body with the necessary amount of phyto-estrogens, which act as a natural catalyst for the production of hyaluronic acid. Those who are categorically against drinking wine are recommended to drink grape juice (natural).

Everyone should know which fruits contain components that promote the body's production of hyaluronic acid. The burdock is named the champion catalyst here. Burdock extract can be purchased in pharmacies and consumed in small quantities daily as food. It is also useful to brew tea with the addition of dried and crushed burdock.

Vitamins C and P

Knowing which foods contain hyaluronate, you should also remember that consuming them in food does not guarantee your skin immediate relief from sagging and other signs of aging. This is easily explained by the fact that the body into which hyaluronic acid enters makes its own decision about its appropriate use. For example, if you ate a portion of rich jellied meat after a long diet for weight loss, your body will most likely send the substance it needs from the outside to the joints and cartilage that urgently need it.

But there is no point in despair, since regular consumption of products containing hyaluronic acid will sooner or later provide the joints with the necessary lubrication. Then, you can expect that the brain will begin to send appropriate signals to restore skin balance. In addition, you should know which foods contain phyto-estrogens, which provoke the body to synthesize the amount of this acid it needs. It is also necessary to take into account cosmetic creams and lotions that contain this important component for preserving youth.

When choosing creams with hyaluronic acid, remember in what proportions this substance should be in their composition. If it is not listed in the first rows, but somewhere at the end of the list, then you should turn your attention to a product from another company or category. Thus, ensuring that you have the correct and balanced diet, and not forgetting about cosmetic procedures, you will be able to push away worries about approaching old age.

In addition to knowing what products you can find hyaluronic acid in, you need to provide yourself with knowledge about those vitamins that help preserve, preserve and synthesize this acid. We are talking about vitamin C and vitamin P (rutin). The ideal option is to consume foods containing these vitamins while simultaneously eating foods rich in hyaluronic acid.

Vitamin P is a substance that is not produced by the human body on its own. However, the importance of routine cannot be overestimated. It helps improve the condition of capillary walls, increases the elasticity of capillaries and their strength, slows down the heart rate, and reduces blood pressure. The recommended daily intake of rutin (60 mg) can reduce intraocular pressure.

Rutin is involved in the processes of bile formation and regulates daily norm urination, having a stimulating effect on the functions of the adrenal cortex. It belongs to the substances analgesic and decongestant. Vitamin P is able to inhibit the production of serotonin and histamine, and also accelerates the treatment of allergic diseases.

Vitamin P is found in the following foods:

  • chokeberry;
  • orange;
  • mandarin;
  • lemon;
  • cherry;
  • grape;
  • plum;
  • apples;
  • apricots;
  • raspberries;
  • black currant;
  • Bulgarian pepper;
  • tomatoes;
  • sorrel;
  • garlic;
  • beet;
  • cabbage;
  • buckwheat group;
  • green tea, etc.

Everyone without exception knows about the benefits of vitamin C (ascorbic acid). Ascorbic acid takes an active part in the body's recovery processes, energy production and strengthening the immune system. If there is little vitamin C in the body, the risk of contracting viral infections increases, cartilage tissue becomes less elastic, which leads to difficulty moving and bleeding gums. The general condition of the body with a lack of this vitamin worsens, so its reserves should be replenished regularly.

It should be noted that the same fruits, vegetables and herbs that contain vitamin P also contain high levels of vitamin C. This greatly simplifies the issue of finding sources of these vitamins, which are especially important for preserving the “reserves” of hyaluronic acid in the body.


The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Hyaluronic acid is a polymer molecule consisting of small compounds with a carbohydrate structure. This compound was discovered about 75 years ago, and is still being intensively studied by chemists, biologists, pharmacists, doctors and scientists in other biomedical specialties. The physical properties of hyaluronic acid are unique - it is capable of holding water molecules, forming a gel-like structure, and in addition, this compound is involved in many important processes in the human and animal body, such as cell division and migration, gene switching, wound healing, fertilization, growth and development of the fetus, the formation of malignant tumors, etc.

Currently, hyaluronic acid is widely used in aesthetic medicine (it is part of cosmetic products such as creams, masks and others, and is also used for biorevitalization procedures and other manipulations aimed at slowing down the aging process and maintaining youthful tissues). In addition to the aesthetic field, hyaluronic acid is widely used in medical practice, for example, in the treatment of eye and joint diseases, in the complex therapy of malignant tumors, in wound healing and in immunology. Let's consider the properties and use of hyaluronic acid in various fields (both aesthetic and medical).

Hyaluronic acid - general characteristics, properties and methods of production

Hyaluronic acid is a polysaccharide, which means that its molecule consists of many identical small fragments, which in their structure are carbohydrates (simple saccharides). Simple sugars join together in a chain and form a long molecule of hyaluronic acid. Depending on the number of fragments that make up the hyaluronic acid molecule, it can have different weights and lengths.

Based on the mass of the molecule, two types of hyaluronic acid are distinguished - high molecular weight And low molecular weight. High molecular weight varieties of hyaluronic acid are molecules with a mass of more than 300 kDa. All hyaluronic acid molecules with a mass of less than 300 kDa are classified as low molecular weight. Both types of substance have a number of identical properties, but at the same time some others physical properties and the biological roles of high molecular weight and low molecular weight hyaluronic acids are different.

Thus, both high and low molecular weight hyaluronic acid are able to bind and retain water molecules, forming a jelly-like mass. This jelly-like mass has a certain viscosity, allowing it to serve as an ideal substrate for any fluids and lubricants in the body (for example, saliva, vaginal and joint lubrication, amniotic fluid etc.), as well as for the extracellular matrix, in which biochemical reactions occur and other important processes take place. The degree of viscosity of the jelly-like mass formed by hyaluronic acid depends on its mass. The greater the molecular weight of the hyaluronic acid molecule, the more viscous will be the jelly-like mass formed by it in combination with water.

The extracellular matrix, formed by a jelly-like mass of water retained by hyaluronic acid, is a unique environment that connects the cells of organs and systems with each other, and also ensures their interaction. Cells and biologically active substances move through the intercellular matrix, entering it from blood vessels. It is thanks to the jelly-like viscous matrix that various substances can reach every cell of an organ or tissue, even if there is no blood vessel passing next to it. That is, some substance or cell exits a blood vessel into the intercellular matrix and passes through it to cellular structures lying deep in the tissues and not in contact with the blood vessels.

In addition, cell waste products, toxins of viruses and bacteria, as well as dead cellular structures are removed from organs and tissues precisely through the intercellular matrix. First, they enter the intercellular substance, then move along it towards the lymphatic or blood vessels, upon reaching which they penetrate into them and are finally eliminated from the body. Such movement between cells in the intercellular matrix is ​​possible precisely due to its jelly-like consistency provided by hyaluronic acid.

In addition, hyaluronic acid is a necessary component of intra-articular lubrication and eye fluid, and is also part of the dermis and connective tissue. This compound imparts viscosity to intra-articular lubricant and eye fluid, ensuring their optimal properties. In the dermis, hyaluronic acid holds collagen and elastin fibers in correct position, thereby maintaining turgor, elasticity and youth of the skin. In addition, by binding water, hyaluronic acid provides the optimal amount of moisture in the skin, which also prevents aging and the appearance of wrinkles. In connective tissue, hyaluronic acid also ensures its turgor, elasticity, extensibility and sufficient moisture.

With a lack of hyaluronic acid, tissues dry out due to a lack of water, which is not retained in them. As a result, tissues become thinner, brittle, inelastic and easily broken, which leads to their aging and the development of various diseases. Hyaluronic acid also takes part in a number of very important processes, such as cell migration and reproduction, gene switching, conception and subsequent growth of the fetus, the formation of malignant tumors, the development of the immune response, etc. Thus, it is simply impossible to overestimate the properties of hyaluronic acid necessary for the normal functioning of organs and tissues at the cellular level.

The body of a person weighing 70 kg constantly contains about 15 grams of hyaluronic acid. Moreover, every day approximately 1/3 of the total amount of hyaluronic acid found in various organs and tissues is broken down and utilized, and new molecules are formed instead. The half-life of hyaluronic acid molecules in joint lubricants ranges from 1 to 30 weeks, in the epidermis and dermis - 1 - 2 days, and in the blood - several minutes. With age, the body loses the ability to synthesize hyaluronic acid in the required quantity, as a result of which the aging process begins. That is why, to slow down aging, mature people need to obtain hyaluronic acid from the outside, from food or from dietary supplements (dietary supplements).

For use in medicine and the aesthetic industry, hyaluronic acid is produced on an industrial scale from two types of raw materials:
1. Vertebrate tissues;
2. Bacteria that form a protective capsule of hyaluronic acid molecules (for example, hemolytic streptococci types A and B).

To obtain hyaluronic acid, the following tissues of vertebrate animals, which contain the largest amounts of this substance, are most often used:

  • Rooster combs;
  • Vitreous body of the eye;
  • Synovial fluid of joints;
  • Hyaline cartilage;
  • Umbilical cord;
  • Epidermis and dermis of the skin;
  • Amniotic fluid.
The optimal raw materials for obtaining hyaluronic acid are the combs of mature chickens and roosters.

Bacteria for the production of hyaluronic acid are used as follows: the required strain is placed on a nutrient medium and provided with ideal conditions for reproduction. When the nutrient medium becomes viscous, this means that the bacteria have produced a sufficiently large amount of hyaluronic acid, which only needs to be isolated and cleared of impurities.

Hyaluronic acid, isolated from animal raw materials and bacteria, has a significant drawback - it contains impurities of proteins and peptides, which cannot be completely removed even after special treatment. These proteins and peptides can provoke allergic reactions in people, which narrows the scope of application of hyaluronic acid.

Ready-made hyaluronic acid is produced by pharmaceutical factories in the form of powders and granules containing molecules of varying weights. These powders are used to prepare solutions, which are then added to creams, masks, medications, etc. Before use, prepared solutions of hyaluronic acid are sterilized in autoclaves.

Biological role of hyaluronic acid

Hyaluronic acid is a polysaccharide with a high degree of hydration (bound to water) and is part of the intercellular matrix, due to which it has very diverse functions and takes part in the processes of reproduction, migration, recognition and differentiation of cells of various organs and tissues.

Depending on the number and size of hyaluronic acid molecules in the intercellular matrix, gels of varying degrees of viscosity are formed, which further determine the properties and functions of tissues, organs, and systems. Thus, gels formed by hyaluronic acid determine the amount of water in the tissue, the intensity of ion exchange in cells (potassium, sodium, magnesium, zinc, etc.), the rate of transport of various biologically active substances and toxins, the impermeability of the medium to large molecules and cells, and etc.

The ability of hyaluronic acid to make any part of the gel medium of the intercellular matrix impermeable to large molecules provides tissues with protection from toxins and the penetration of microbes (bacteria, protozoa and fungi).

Retention of a large amount of water by hyaluronic acid creates incompressibility and swelling effects, on the basis of which effective resistance to various mechanical effects aimed at compressing tissues and organs is realized. Thanks to this, organs and tissues retain their shape and are not subject to compression, and, consequently, injury. It is thanks to this effect of hyaluronic acid that we can, for example, squeeze the skin with our fingers without damaging its structures.

The viscosity of the joint fluid created by hyaluronic acid allows it to act as a lubricant for the rubbing cartilaginous surfaces of the two articulating bones, and also reduce the negative effects of excess pressure.

It is an aqueous solution of hyaluronic acid that fills the vitreous body of the eye, as well as an integral part of other structures of this organ. Hyaluronic acid is very important for the normal functioning of the eye, since its solutions are transparent and stable, which creates the necessary environment for the passage of a light beam to the retina without any distortion.

Hyaluronic acid plays a huge role in egg fertilization. The fact is that when leaving the ovary during ovulation, the egg is covered with two structures that protect it, called the zona pellucida and the corona radiata. Both the zona pellucida and the corona radiata in the intercellular matrix contain a large amount of hyaluronic acid, thanks to which they, in fact, exist. The egg is capable of fertilization only as long as its corona radiata and zona pellucida are completely intact. Once the corona radiata is destroyed in the fallopian tube, the egg will lose its ability to fertilize and die. Thus, if there is a lack of hyaluronic acid in the body, even healthy and full-fledged eggs can be useless, since they quickly die in the fallopian tube, being unable to be fertilized by sperm.

In addition, after fertilization, the remains of the zona pellucida with hyaluronic acid prevent the already fertilized egg from sticking to the walls of the fallopian tube, which is a mechanism for preventing ectopic pregnancy.

Hyaluronic acid also plays a huge role in subsequent fetal growth after fertilization. The fact is that whole molecules and fragments of hyaluronic acid trigger the process of division, migration and maturation of cells in the fertilized egg, as well as the formation of organs and systems from them.

Inside cells, hyaluronic acid takes part in the process of division, that is, it is necessary for the reproduction and formation of new cellular elements to replace old or damaged ones. Thanks to this effect, hyaluronic acid stimulates the process of repairing damage in organs and tissues. For example, in case of bone fractures, it is hyaluronic acid that stimulates the rapid fusion of fragments. Stimulation of repair processes occurs not only due to the activation of cell division, but also due to the ability of hyaluronic acid to activate the growth of blood vessels, which are necessary for newly forming tissue. Unfortunately, the ability of hyaluronic acid to stimulate the growth of blood vessels can also play a negative role, for example, during the growth of a malignant tumor. After all, the faster new vessels that feed the tumor are formed, the faster it increases in size, and the sooner it metastasizes.

Hyaluronic acid is also a component of innate immunity, which every person possesses from the moment of birth. In the skin and connective tissue, hyaluronic acid performs a number of very important functions due to the fact that it maintains collagen and elastin threads in their normal position and condition. Thus, this molecule protects the skin, preventing pathogenic microbes from penetrating deeper from its surface in the presence of damage (wounds, scratches, etc.). In addition, hyaluronic acid maintains the hydrobalance of the dermis and epidermis, reducing water evaporation and at the same time helping to attract and retain moisture from the air on the skin surface. Thanks to these properties, hyaluronic acid moisturizes the skin and also makes it smooth and elastic, preventing damage, thinning and drying, and thereby slowing down aging.

Summarizing the above, we can summarize that All types of hyaluronic acid have the following properties:

  • Maintains and restores the normal degree of hydration (moisture) of the skin;
  • Improves the elasticity of tissues, including skin;
  • Normalizes tissue tone, including skin;
  • Improves microcirculation;
  • Accelerates the process of cell renewal in all tissues, including the skin;
  • Relieves inflammation and eliminates swelling of the skin.
However, the described effects are not fully inherent in all types of hyaluronic acid. Thus, high-molecular types of hyaluronic acid have some effects, while low- and medium-molecular types have others.

Low molecular weight varieties of hyaluronic acid, having a mass of less than 30 kDa, have the following properties:

  • They pass through barriers formed by cell membranes, as a result of which they can penetrate from the surface of the skin into the deep layers of the dermis;
  • Stimulate the growth of lymphatic and blood vessels;
  • Improve microcirculation and skin nutrition.
Medium molecular varieties of hyaluronic acid, having a mass from 30 to 100 kDa, have the following properties:
  • Accelerate wound healing;
  • Stimulate cell division;
  • Accelerate cell migration into the wound.
High molecular weight varieties of hyaluronic acid, having a molecular mass from 500 to 730 kDa, have the following properties:
  • Suppress cell division and migration to the area of ​​damage;
  • Do not penetrate from the surface of the skin into the deeper layers;
  • Suppress the growth of lymphatic and blood vessels;
  • Stop inflammation;
  • Prevents cartilage destruction.

Areas of application of hyaluronic acid

Hyaluronic acid is widely used in the aesthetic field and in applied medicine in areas such as ophthalmology, arthrology, oncology, wound healing and immunology. Let's look at ways to use hyaluronic acid in various areas.

Hyaluronic acid in the aesthetic field

Modern aesthetic medicine and cosmetology cannot be imagined without hyaluronic acid, since it is used very widely. Thus, in cosmetology, hyaluronic acid is included in various creams, serums, masks, gels and other products designed to moisturize, rejuvenate or reduce the severity of age-related changes in the skin.

In aesthetic medicine, hyaluronic acid is the most popular product used to rejuvenate the skin, as well as eliminate age-related changes and “minus tissue” defects that have arisen after surgical interventions. Hyaluronic acid is used in injection rejuvenation techniques, such as filler implantation, biorevitalization and mesotherapy. The widespread use of this compound in injection methods of aesthetic medicine is due to a number of factors: firstly, the introduction of hyaluronic acid into the skin is safe, since allergic reactions to the drug do not occur; secondly, an implant made from a long hyaluronic acid molecule lasts for a long time, that is, the effect of the procedure lasts from 1 to 1.5 years. Finally, hyaluronic acid injections are easy to administer and painless.

Thus, it is obvious that hyaluronic acid is a very important component of modern cosmetics and a necessary substance for a number of non-surgical skin rejuvenation methods. Let's take a closer look at how hyaluronic acid is used in cosmetic products and used in non-surgical skin rejuvenation methods.

Injections with hyaluronic acid (hyaluronic acid injections)

The general name “hyaluronic acid injections” usually refers to several methods of non-surgical skin rejuvenation and elimination of the severity of age-related changes, which are united by the common essence of their production - the introduction of “hyaluronic acid” preparations into the structures of the skin using injections. That is, hyaluronic acid is injected into the skin using an ordinary syringe or a special roller. After injections of hyaluronic acid, made by any method, a person’s skin is smoothed, wrinkles either completely disappear or their severity becomes less pronounced, turgor appears and sagging is eliminated, and the degree of moisture in the structures of the skin increases. After all, skin aging, the appearance of wrinkles, sagging, dryness and dullness are caused precisely by a deficiency or decrease in the amount of hyaluronic acid in the deep layers of the skin, and therefore its management is effective way rejuvenation and elimination of dryness.

Methods collectively called “hyaluronic acid injections” include the following procedures:

  • Biorevitalization;
  • Bioreparation;
  • Contour plastic with fillers.
These “injection” procedures differ from each other in the types of hyaluronic acid used for their production, the injection technique, as well as indications and contraindications for use.

So, mesotherapy produced according to the principle “rarely, little, in the right place.” That is, hyaluronic acid is injected in small quantities only into those areas that need correction (for example, in the area of ​​wrinkles, etc.). In addition, the "rare" principle means that injections are given once every few days. Mesotherapy has a cumulative effect due to the fact that hyaluronic acid is introduced in small quantities, and therefore, to obtain a good result, it is necessary to make several injections into the same area. The effect of mesotherapy lasts for several months.

Biorevitalization is performed using the same injection techniques (papular, tracer, canal) as mesotherapy, but large quantities of high molecular weight hyaluronic acid are used. Therefore, biorevitalization is performed at one time. This procedure gives immediate and delayed results. Immediate results include smoothing of wrinkles, which is noticeable immediately after the procedure. However, this immediate effect lasts approximately 1 – 2 weeks, after which it disappears. Next, the hyaluronic acid introduced into the skin is destroyed by special enzymes, and short fragmentary molecules are formed. These molecules stimulate the production of your own hyaluronic acid, collagen and elastin, which is the main goal of the biorevitalization procedure, since as a result of this process restoration and rejuvenation of the skin occurs. It is the restoration of the structures of aging skin that is the long-term result of biorevitalization, which is manifested by an improvement in tone, the disappearance of sagging, and a decrease in the number and depth of wrinkles. Long-term results of biorevitalization last for 1 – 1.5 years.

Bioreparation is a procedure similar to biorevitalization. However, bioreparation differs from biorevitalization in that its production uses complex preparations containing, in addition to hyaluronic acid, vitamins, minerals and other biologically active substances. As a result of the introduction of hyaluronic acid, vitamins and minerals into the skin structures, a long-lasting and pronounced rejuvenation effect is achieved, and minor unevenness and defects of the skin (for example, scars, acne marks, etc.) are eliminated.

Contour plastic with fillers is the introduction of special long threads of high molecular weight hyaluronic acid stitched together into certain areas of the skin that require correction. These threads are called fillers and are located on problem areas. Thanks to the introduction of fillers, you can correct the line of your cheekbones, the shape of your face, eliminate bags under the eyes, etc.

All hyaluronic acid injection methods are performed under local anesthesia, so the procedures themselves are painless. However, after the local anesthetic wears off, you may experience mild pain for 2 to 4 days, as well as persistent swelling and redness of the skin.

Lip augmentation with hyaluronic acid

This procedure is a private variant of hyaluronic acid injections, which are performed in the lip contour area. When hyaluronic acid in the form of fillers is injected into the lips, it fills the tissue and attracts water, which leads to an increase in their volume, and also makes the contour clearer and more beautiful. As a result, lips become fuller, plump and smooth with a clear contour, and also acquire a rich color. The achieved result lasts approximately 8 – 18 months.

During the procedure, a small volume of hyaluronic acid is injected into the lips through puncture injections. Depending on the amount of hyaluronic acid injected, lip volume can be increased moderately or significantly. The more hyaluronic acid is introduced, the more the lip volume will increase.

The procedure itself lasts half an hour and is carried out under local anesthesia, and the full result is formed in two days. After lip augmentation with hyaluronic acid, swelling, redness and painful sensations, which then go away completely.

Hyaluronic acid under the eyes

Hyaluronic acid can be used to eliminate wrinkles and dark circles under the eyes, as well as give thin skin this area of ​​elasticity, firmness and increasing the degree of moisture. Hyaluronic acid under the eyes can be used both in the form of injections and as part of special creams, serums, gels or mousses containing it as an active component.

Indications and contraindications for hyaluronic acid injections (including for lip augmentation)

Hyaluronic acid injections using various methods are indicated in the following cases:
  • Dry and dehydrated skin;
  • Loose skin on the face, abdomen, thighs and shoulders;
  • Wrinkles in the eye area, oval face and décolleté;
  • Circles under the eyes;
  • Dull and unhealthy complexion;
  • Enlarged pores on the skin of the face;
  • Increased sebum production;
  • Facelift;
  • Improving the cheekbone line;
  • Elimination of wrinkles;
  • Increasing the amount of moisture in the skin;
  • Increased skin elasticity and turgor;
  • Normalization of skin texture;
  • Increasing volume and improving lip contour.
Hyaluronic acid injections are contraindicated in the following cases:
  • Intolerance or allergic reactions to hyaluronic acid;
  • During pregnancy and breastfeeding ;
  • Acute period any acute and infectious diseases;
  • Autoimmune diseases;
  • Connective tissue pathology;
  • Malignant tumors;
  • Hypertonic disease;
  • Tendency to form scars on the skin;
  • Diabetic angiopathy;
  • Blood clotting disorders;
  • The presence of inflammation or moles in the area of ​​the intended injections;
  • Skin diseases;
  • Taking medications that affect blood clotting (anticoagulants, antiplatelet agents, etc.).

Preparations for injections of hyaluronic acid

Currently, a variety of drugs produced in the world are used for hyaluronic acid injections. different countries and designed for various purposes. Below in the table we provide a list of the main high-quality certified hyaluronic acid preparations, indicating the indications for their use and the duration of the achieved effect.
Hyaluronic acid preparation Indications for use of the drug Duration of the achieved effect
VariodermCorrection of medium and deep wrinkles
Lip contour correction
6 – 12 months
Varioderm FinelineElimination of superficial wrinkles
Correction of crow's feet
Correction of the red border of the lips
6 – 12 months
Varioderm PlusCorrection of deep wrinkles
Correction of facial oval
6 – 12 months
Varioderm SubdermalCorrection of very deep wrinkles
Increase in tissue volume
6 – 12 months
Hylaform (Hylan-B age)Lip shape correction
12 months
Hyalite (Puragen)Lip shape correction
Elimination of nasolabial folds
12 months
Teosyal Global ActionCorrection of medium wrinkles12 months
Teosyal Deep LinesCorrection of deep wrinkles and skin folds12 months
Teosyal KissCorrection of lip volume and contour12 months
Prevelle3 – 6 months
CaptiqueCorrection of fine and medium wrinkles3 – 6 months
RepleriCorrection of medium and deep wrinkles12 – 18 months
Juvederm Ultra6 – 8 months
Juvederm Ultra PlusCorrection of medium to deep wrinkles and folds6 – 12 months
Sirgiderm 18Correction of fine wrinkles6 months
Sirgiderm 30Elimination of deep skin depression
Replenishment of tissue volume deficit
9 months
Sirgiderm 24 XPElimination of moderate skin depression
Lip contour correction
9 months
Sirgiderm 30 XPElimination of deep and moderate skin depression
Replenishment of tissue volume deficit
Correction of lip contour and shape
9 months
Belotero BasicScar removal
Correction of deep and medium wrinkles or furrows
Correction of facial contours
Increase in volume and correction of lip contour
6 – 9 months
Belotero SoftCorrection of fine superficial wrinkles6 – 9 months
Joliderm 24+Correction of deep expression wrinkles
Correction and restoration of lip contour
6 – 9 months
Jolidermis 24Correction of medium and deep expression wrinkles6 – 9 months
Joliderm 18Correction of fine wrinkles6 – 9 months
RestylaneCorrection of moderate wrinkles6 – 12 months
Restylane LippIncreased lip volume
Correction of the red border of the lips
6 – 12 months
Restylane PerlaneCorrection of deep folds
Correction of facial oval
6 – 12 months
Restylane SubQElimination of age-related tissue volume deficit
Elimination of soft tissue asymmetry
12 – 18 months
Restylane TouchCorrection of very fine wrinkles (including in the orbital area of ​​the eye and mouth)6 months
Eugulon BCorrection of fine and deep wrinkles and post-acne6 months
HyaluformCorrection of fine wrinkles6 – 7 months
Hyaluform 1.8%Correction of average wrinkles and folds8 – 9 months
Hyaluform 2.5%Elimination of tissue volume deficit6 – 8 months
Gialripayer-0.1Correction of fine and deep wrinkles10 – 14 months

Hyaluronic acid before and after – photo


This photograph shows the effect achieved by injections of hyaluronic acid produced using the biorevitalization method.


This photo shows the effect of hyaluronic acid injections with Restilane.

Lips after hyaluronic acid – photo



This photo shows the effect of increasing lip volume using hyaluronic acid.

Cream, serum and masks with hyaluronic acid

Various creams, masks, serums and other cosmetic products with hyaluronic acid are intended for external use to moisturize the skin, as well as reduce the severity of age-related changes. Cosmetics with hyaluronic acid tighten the skin, reduce sagging, rosacea and the size of enlarged pores, as well as even out the complexion and improve the texture of the skin. However, in order to get a visible effect from cosmetics with hyaluronic acid, they must be used regularly for at least a month.

When choosing a cosmetic product, you need to focus on the quantity and quality of hyaluronic acid in it. Thus, serums contain the highest concentration of hyaluronic acid, so these cosmetic products are recommended to be chosen for the care of skin in poor condition, as well as to obtain the fastest possible effect. It is recommended to use serums with hyaluronic acid at the initial stage, and then switch to using creams with hyaluronic acid.

Creams may contain high or low molecular weight hyaluronic acid. High-molecular hyaluronic acid in the creams covers the skin with an invisible film, from which it is absorbed into the upper layers of the epidermis, making it moisturized, tightened, with an even and radiant color. Low molecular weight hyaluronic acid is able to be absorbed from the surface into the deep layers of the skin, where it stimulates the production of collagen and elastin, which leads to a more pronounced and lasting effect. However, creams containing low molecular weight hyaluronic acid are much more expensive than cosmetics containing a high molecular weight form of “hyaluronic acid”. Therefore, to correct superficial age-related changes, it is optimal to use creams with high molecular weight hyaluronic acid. Accordingly, to correct and reduce the severity of deep age-related changes, it is necessary to use creams with low molecular weight hyaluronic acid.

Masks with hyaluronic acid are used according to the same principles as creams. Creams and serums can be used daily, and masks – 1 – 2 times a week. All products with hyaluronic acid must be used only at above-zero temperatures, since in the cold its molecules crystallize and can damage the skin. Therefore, in winter, it is recommended to apply products with hyaluronic acid only in the evening, when you no longer plan to go outside.

However, it must be remembered that cosmetics with hyaluronic acid are not recommended for use by people under 25 years of age, as this may cause the opposite effect. The fact is that in young women, the skin itself produces a sufficient amount of hyaluronic acid and does not need intensive care, and therefore the constant supply of this substance from the outside can lead to the fact that the skin stops producing it. As a result, premature aging of the skin will occur.

Currently, creams, serums, masks and other cosmetics are produced by many companies, so purchasing them is not a problem. Some of the best cosmetics with hyaluronic acid are creams, masks, mousses and serums produced by European, Asian and American companies.

Hyaluronic acid preparations for facial skin: application (injection), effects, possible complications, recommendations of a dermatocosmetologist - video

Creams and injections with hyaluronic acid: how they work, in what cases they are used - video

Creams for moisturizing dry skin: with hyaluronic acid, with film-forming substances, with hydroxy acids - video

What is the difference between the effects of cream, serum and hyaluronic acid injections (answer from a cosmetologist) - video

Hyaluronic acid for joints

Healthy joints always contain a small amount of fluid, which acts as a lubricant. This liquid contains hyaluronic acid, which gives it the necessary properties. At various diseases joints, the concentration of hyaluronic acid in the joint fluid decreases by 2–4 times. Therefore, a method of treating joint diseases is currently being successfully used, which consists of introducing high-molecular hyaluronic acid into its cavity.

When hyaluronic acid is injected into a joint for osteoarthritis, pain is relieved and its functional activity is improved, which allows a person to move normally and lead a normal lifestyle. In addition, the use of hyaluronic acid restores the properties of intra-articular fluid, suppresses the inflammatory process and stimulates the restoration of normal tissue structure.

Currently, the following hyaluronic acid preparations are used for joint diseases:

  • Viscorneal forto;
  • Viscosil;
  • Sinvisc (Gilan G-F 20);
  • Sinokrom;
  • Suplazin;
  • Ostenil.
It should be remembered that the greater the molecular weight of hyaluronic acid injected into the joint, the longer the therapeutic effect. Therefore, to obtain a long-term therapeutic effect, it is necessary to choose preparations containing hyaluronic acid with the highest molecular weight.

Hyaluronic acid in ophthalmology

Hyaluronic acid preparations are widely used in local and systemic treatment of eye diseases. Thus, hyaluronic acid is included in the composition of “artificial tears” eye drops intended for the treatment of dry cornea. Hyaluronic acid is also used for eye surgery in order to create an optimal operating environment and protect tissue from accidental damage.

Hyaluronic acid in wound healing

Hyaluronic acid suppresses the inflammatory process and activates the processes of restoration of normal tissue structure, due to which it is successfully used in the healing of wounds, burns and trophic ulcers. To heal wounds, hyaluronic acid is injected into a special dressing material, which is used to cover various damage to the skin, and the dressings are periodically changed.

Bioexplants with hyaluronic acid (thin film) are used to cover sutures on the intestines after surgical interventions, which significantly accelerates wound healing and tissue restoration. In addition, bioexplants with hyaluronic acid are used during laparoscopic operations to cover intestinal loops to prevent accidental injury.

Hyaluronic acid - reviews

Most reviews of hyaluronic acid (from 85 to 90%) in cosmetics are positive, due to the visible aesthetic effect. Reviews indicate that salon procedures with hyaluronic acid very effectively moisturize the skin, make it smoother and more elastic, as a result of which fine wrinkles are smoothed out and new ones do not form. In addition, many reviews indicate that the use of creams with hyaluronic acid leads to the same effect as salon procedures, but only more slowly. If the effect of salon procedure noticeable immediately, then when using creams or masks it appears only after a month.

Even a person far from the world of fashion, beauty and beauty salons knows the phrase “hyaluronic acid”. Some are sure that this is a means to smooth out wrinkles and proof of this is a cream with hyaluronic acid. Others believe that it is a means of enlarging the lips. Still others think that this is “some kind of medicine,” since hyaluronic acid in tablets is sold in pharmacies and is “injected” into the knee joints. Each of the opinions is correct, but not complete.

Hyaluronic acid is a substance that is produced in the human body and serves many purposes. The hyaluronic acid molecule is a spiral-shaped polymer that “attracts and binds” water molecules, forming a gel-like mass. Hyaluronic acid ensures the content of the required amount of moisture in the intercellular space, in connective tissue, epithelium, nerve fibers and in all mucous substances of the body.

Hyaluronic acid - history of discovery, use

A hundred years ago, hyaluronic acid (HA) was isolated from umbilical cord blood and vitreous humor. The substance, which is a polysaccharide, has a long linear molecule and a large molecular weight. A molecular chain consisting of groups of atoms is capable of bending, compressing and stretching, which ensures its elasticity. This property of HA ensures joint mobility, elasticity and firmness of the skin and ligaments.

The hygroscopicity of HA is unique. One molecule of it is capable of “binding and holding” from five hundred to a thousand molecules of water. This property is used in medicine and cosmetology.

Hyaluronic acid is not species specific - it is the same for all mammals, including humans.

The first hyaluronic acid was synthesized from rooster combs. The resulting drugs were used to treat the eyes. Hyaluronic acid gel provided the most favorable environment during manipulations on the cornea, creating and maintaining the necessary, close to natural, hydration.

Until 1982, HA was used exclusively in medicine for the treatment of joint diseases and in ophthalmology. Hyaluronic acid for the face was first tested by Japanese cosmetologists, who are still leaders in research on this topic.

Initially, hyaluronic acid was not synthesized artificially, but was isolated from organic sources. It was “extracted” from rooster combs and umbilical cord blood. The biological role of hyaluronic acid is that it plays the role of a buffer between external influences on human tissues and organs and their ability to resist this influence. So, we can squeeze the skin of the body with our fingers, and it will not be deformed. As soon as we weaken the impact, the skin returns to its original shape.

The large size of the HA molecule determines its protective properties, but is an obstacle to its introduction into the body from the outside, locally, through the skin. This hinders its wider use in aesthetic medicine and cosmetology.

Japanese biochemists have developed technologies for producing a pure, hypoallergenic substance through the “work” of lactic bacteria. A serious task for scientists was to reduce the size of the molecule of an artificially created drug. This is important so that the molecule can overcome skin pores that are too small for it.

The problem of penetration of hyaluronic acid into the body from the outside through the skin is in the process of being solved, although great progress has already been made in this direction. It is thanks to a serious reduction in the molecular size and mass of molecules of an artificially obtained product that cream with hyaluronic acid is used in cosmetology.

Hyaluronic acid in medicine

Hyaluronic acid ensures the vital activity of the articular apparatus, the eyeball, and is one of the main components of extracellular tissues, which ensures their supply of water and nutrients.

The main areas of use of hyaluronic acid in medicine:

  1. Treatment of joints;
  2. Ophthalmology;
  3. Dosed release and transportation of drugs;
  4. Wound healing.

Therapy for degenerative joint diseases

The unique properties of HA allow it to be used for the treatment and replacement of joints. Research shows that the intrinsic acid content of synovial fluid (the thick substance in the joint that allows freedom of movement and protects cartilage) is fundamental.

Injections of hyaluronic acid directly into the joint (or replacement of synovial fluid) enhance the protective function of synovial fluid, make it more viscous, and relieve inflammation. The effect of a course of CG injections for arthrosis lasts about a year. The classic treatment regimen is 5-7 injections of sodium hyaluronate, given once a week. For the treatment of the initial stage of degenerative changes in the joint, 1 course is sufficient. Treatment for more serious lesions may last up to 4 years. Injections are carried out in a clinical setting, under ultrasound control.

Along with injections, hyaluronic acid is offered in the pharmacy in the form of tablets, gels, creams, and capsules. These HA preparations for the treatment of joints have much less effectiveness, since their transport to the sore spot is associated with a number of changes during absorption when taken orally.

The local effect of creams or gel in terms of delivering HA directly to the joint seems unlikely. There have been no serious scientific studies on the effect of oral medications or ointments on the composition of synovial fluid.

Hyaluronic acid injections are not performed if there is an active inflammatory process in the joint. Slight discomfort, a burning sensation in the periarticular tissues or swelling after the injection are considered a normal reaction. The availability of injection therapy is limited by the price of hyaluronic acid in pharmacies. One injection costs 2-3 thousand rubles, depending on the drug chosen.

The first HA preparation was isolated from the vitreous humor of the bovine eye. The medicine was used to treat chronic inflammatory eye diseases and in eye surgery.

In modern ophthalmology, hyaluronic acid is used:


In ophthalmic surgery, HA is injected into the vitreous body to protect intact eye tissue and facilitate manipulations such as lens replacement, cataract removal, and corneal transplantation.

Treatment of “dry eye” syndrome, when the eyes quickly get tired, turn red, and hurt, is becoming increasingly important today. Young people, over 30 years old, are forced to resort to preparations based on hyaluronic acid, since their eyes become overtired by the middle of the day of working in the office, with documents, at the computer, and there is not enough natural moisture. This is especially felt by people who wear contact lenses to correct their vision.

To prevent the occurrence of inflammatory diseases and to protect the eyes from drying out, artificial tear drops based on hyaluronic acid have been created. They create a protective film on the surface of the eyeball, complementing the natural hydration of the eyes.

Inserting hyaluronic acid into the eyes when the cornea is damaged promotes comfortable, natural healing. This is relevant for people who, due to the nature of their work, risk getting burns or microtrauma to the eyes.

Use of HA in drug transport

The unique qualities of hyaluronic acid to bind dissolved substances and change itself under the influence of solvents make it a valuable drug for the dosed release of another drug or/and its transportation to a damaged organ. The HA-bound drug is injected into the affected area, where it is gradually released. This technique ensures a constant effect of the drug on the pathological focus without the risk of overdose.

Preparations based on hyaluronic acid are used in the treatment of immunodeficiency conditions and tumor pathologies. Hyaluronic acid is widely used in the creation of topical surface preparations. Here the active substance penetrates the skin by “binding” to HA molecules, which acts like a big locomotive. The absorption and effectiveness of drugs increases 2-3 times compared to conventional use.

Application in wound healing

Hyaluronic acid is used both for healing superficial wounds and for post-operative internal linings on operated areas of the intestine (or other organs).

To heal superficial wounds and burns, HA is introduced into a special dressing material to create a durable antibacterial film that promotes tissue regeneration.

In surgical practice, special film bioexplants based on hyaluronic acid are used. This film is used to cover operated surfaces to isolate tissues, which significantly increases the speed of their recovery. During laparoscopic interventions, bioexplants are used to protect surrounding tissues from accidental damage by the instrument.

Hyaluronic acid in cosmetology

The use of Hyaluronic acid in cosmetology is due to its properties to capture, accumulate and retain moisture, which increases the plastic properties of the skin. The epidermis and its inner layers contain up to one fifth of the body's total moisture reserves. Humidity consists of two differently directed processes - the entry of moisture from the body and its evaporation from the surface layer.

The healthy functioning of the two processes ensures good skin hydration and turgor. The condition of the dermis is affected external factors and internal. If in at a young age If the body quickly compensates for the influence of unfavorable conditions, then with age not only the compensatory capabilities of the body decrease, but also the structure of the skin itself changes, and metabolic functions change.

Decreased peripheral blood flow reduces the supply of nutrients and water to the skin. Protective and water-saving mechanisms work less effectively. The production and content of natural hyaluronic acid decreases.

Cosmetic creams and gels containing hyaluronic acid for the face cover the skin with a thin layer, retaining internal moisture, “catching” moisture from the outside. HA penetrates into the deep layers of the dermis, restoring the structure from the inside.

Overcoming the skin barrier

The question of the penetration of large molecules of hyaluronic acid through relatively small skin pores has not yet found a clear answer. Some argue that the use of creams with hyaluronic acid is effective due to exclusively superficial hydration. Other (and these are the majority) studies confirm the ability of even high-molecular acid to penetrate into the deep layers of the skin, “carrying” with it moisture, nutrients and medicinal substances.

The study was conducted on volunteers who had a “labeled” gel with hyaluronic acid applied to their skin. After 30 minutes, HA molecules were detected in the body of the subjects during autoradiography. Labeled molecules were confirmed by chromatographic analysis of urine, liver samples and skin.

Electrophoresis effectively accelerates the process of penetration of HA through the skin. This procedure helps large molecules overcome it, which greatly increases the effectiveness of such moisturizing and rejuvenating the skin. Large acid molecules accumulate large quantity water and nutrition, it takes longer to release it.

Injections of hyaluronic acid into the facial area using various methods, using different compositions are called “HA injections” in the “common people”.

This concept combines:

Injections with hyaluronic acid are a rather painful procedure, which is performed under local anesthesia. After the effect of the painkiller wears off, the burning sensation and pain may persist for some time. Redness and swelling lasts for 20-3 days.

Reviews about injection facial rejuvenation are predominantly positive. The effect of these procedures is mild, natural preparations are used.

Biorevitalization with hyaluronic acid, the reviews of which are the most impressive, provides a rapid effect when wrinkles disappear immediately after the procedure, and a long-term effect when the effect of HA lasts from a year to a year and a half.

Lip correction

Contour correction and lip augmentation with hyaluronic acid are carried out in the same way as facial correction - using injections of hyaluronic filler. Multiple injections are made along the perimeter of the lips. Correction of the contours and size of the lips is achieved by dosing the injected drug.

The result of the “operation” is an increase in the size of the lips (sometimes significant), giving them swelling, a clear contour and a more saturated color. Swelling and pain after correction can last up to one week. The correction itself lasts from 8 months to one and a half years.

Hyaluronic acid should be administered to the lips or face only in a clinic whose reputation is well known and time-tested. Low-quality drugs administered by an inept hand can disfigure your appearance for a long time.

There are a number of contraindications for injection correction of lip or facial contours:

  • Pregnancy, breastfeeding;
  • Chronic diseases in the acute stage;
  • Blood diseases in which blood clotting is impaired;
  • The presence of Botox or other drugs in the area of ​​intended injection of GC;
  • Exacerbation of herpes;
  • Inflammatory or other skin diseases in the acute stage in the area of ​​drug administration;
  • Anticoagulant therapy at the time of the procedure.

Biorevitalization with hyaluronic acid reviews with photos

Biorevitalization, unlike surgical facial correction, does not have such a long-term effect. However, reviews of the procedure indicate that most women are satisfied with the result. They note that the skin not only tightens, but becomes more youthful and elastic for a long time. The feeling of tightness and sagging disappears from the face.

Small wrinkles are noticeably smoothed out, although large ones are almost unaffected. The good news is that the procedure does not need to be performed often, like mesotherapy. Injections to the face and lips are still painful and do not cause any particular desire to “repeat”.

Cream

Libriderm cream with hyaluronic acid is declared by the manufacturer as moisturizing, nourishing with a high content of HA. It is fragrance-free and supplemented with camelina oil and pomegranate extract. The cream has a light structure, designed specifically for daily use on the face and décolleté.

The composition of the cream provides the maximum possible, comprehensive nutrition of the skin and its long-term hydration. Camelina oil supplies the skin with polyunsaturated fatty acids, which relieve irritation and heal the skin. Pomegranate extract smoothes fine wrinkles and stimulates collagen production.

Libriderm cosmetics with hyaluronic acid are equipped with a special vacuum dispenser, which makes these products the most convenient for daily care.

Despite all the advantages, libriderm hyaluronic cream causes mixed reviews. Consumers note its “unpleasant” smell and the fact that it forms a non-breathable film on the face.

Serum

Serum with hyaluronic acid has an even lighter texture than cream. It is hypoallergenic. Designed for facial skin care, including the area around the eyes. The product is applied daily, after washing, as independent nutrition and care, or followed by application of day cream.

The serum not only nourishes the skin and saturates it with moisture, but also stimulates its regeneration processes.

Non-injection filler

Libriderm hyaluronic filler 3D is a cosmetic line of products for correcting the contours of the face, lips and skin care around the eyes. The series includes night and day creams, lip balm and eye cream.

Night cream-corrector contains three types of hyaluronic acid: high molecular weight, medium molecular weight and low molecular weight. Thanks to this combination of active ingredients, the most complete and deep night restoration of the skin is ensured, its contours are tightened. The cream prevents swelling and stretching of the skin.

Day cream effectively protects the skin from external influences, “locking” natural moisture into it. Protects the skin from photoaging and the formation of small expression wrinkles.

Lip filler balm, after application, gives the lips additional volume. Pink color with a glossy effect gives lips a moisturized and fresh look. The manufacturer claims that with regular use of this product for two months, lips acquire actual additional volume.

The eye cream in this series is positioned as a product that can smooth out the skin around the eyes, including expression wrinkles. Significantly reduces the appearance of under-eye bags. Visually reduces the intensity of dark circles and other signs of age.

The cost of Libriderm cosmetics ranges from 500-800 rubles per unit.

Hyaluronic acid for oral administration

Hyaluronic acid Evalar in capsules or tablets is available in pharmacies. The product is positioned as a dietary supplement that helps saturate the body with missing hyaluronic acid, and therefore moisture.

After taking a dietary supplement, you should not expect instant or even rapid skin rejuvenation or smoothing out wrinkles on the face. Once in the body, hyaluronic acid is sent directly into the joint fluid. After complete saturation of the entire articular apparatus, the drug reaches the eyes, and then only reaches the skin.

Hyaluronic acid Evalar has positive reviews. Given its relatively high cost, the use is considered justified by the majority of women who left reviews on the Internet. Consumers note. that by the end of the course of taking the drug, their skin improved significantly, became more elastic, and stopped peeling. Positive changes affect not only the skin of the face, but also the whole body.

Hyaluronic acid tablets:

  • Helps reduce crunching in joints, increases their mobility, relieves pain;
  • Positively affects the condition of the eyes - they get tired less, the feeling of “sand in the eyes” disappears;
  • The skin of the entire body becomes elastic and youthful.

Achieving the listed effects is possible only with long-term use of tablets or capsules with hyaluronic acid.

About the cost of hyaluronic acid preparations

The price of hyaluronic acid depends on the form of the drug, manufacturer and volume of the product:

  • Hyaluronic acid in a pharmacy, the price of injection ampoules varies from 2 to 5 thousand rubles. for one ampoule;
  • Moisturizing serum is offered from 90 rubles. for 10 ml;
  • The price of a 30 ml bottle of cream varies from 450 rubles. up to 3500 rub.;
  • Tablets and capsules are offered in the range of 1100-1600 rubles. for 30 units

What foods contain hyaluronic acid?

Hyaluronic acid is naturally produced in the body and may be the key to eternal youth. Some products contain hyaluronic acid and can help stimulate its production in the body, resulting in smoother, younger-looking skin, improved vision, and a more flexible and healthy body. Hyaluronic acid is a substance that is found in the structure of the skin, eyes, joints and heart valves, providing lubrication and protection. Bill Sardi, author of Live a Hundred Years Without Aging, explains that hyaluronic acid "is made up of water-based gel-like molecules that are found in abundance in children and young women whose bodies are capable of producing estrogen." As you get older, the level of hyaluronic acid in your body decreases. A person’s skin begins to age, wrinkles appear, vision and joints also begin to show signs of aging, and disturbances in their functioning are observed. Animal Sources of Hyaluronic Acid As Harvey Blatt wrote in his 2008 book The Food of America: What You Don't Know About What You Eat: "The red combs of roosters and hens are one of the world's richest sources of the sugar molecule hyaluronan, a compound , which doctors call the next wrinkle remover after Botox.” Along with red combs, there are other parts of animals that are rich in hyaluronic acid. Animal joints and tendons, just like human joints and tendons, contain hyaluronic acid. Ideal source dishes: broth, stew with bones and joints, tendons, skin. Classic chicken broth is one hundred percent suitable, but it is worth remembering that it greatly raises blood pressure. Soy Products Soybeans contain high levels of phyto-estrogens, plant sources of estrogen that act like estrogens in the body. Estrogen helps the body produce more hyaluronic acid. Thus, consuming soy products such as tofu and soy milk can be a good source of phyto-estrogens. Yakult scientists at the Central Institute of Microbiological Research, Tokyo, Japan have shown that soy milk fermented with bifidobacteria (“friendly bacteria”) significantly increases the production of hyaluronic acid when applied topically to the skin for two weeks. This only applies to fermented soy milk extract. Red Wine Another phyto-estrogen found in the skins of grapes and red wine, it helps stimulate the formation of hyaluronic acid in the body. In 1997, researchers at Northwestern University School of Medicine learned that red wine contains resveratrol, concentrated primarily in the skin of the grape. Red wine or red grape juice will help increase estrogen production, which stimulates the body to produce more hyaluronic acid. Starchy Root Vegetables In November 2000, ABC News Prime Time reporters profiled the people living in Yuzurihara, a village in Japan known as the Long Life Village. All residents have smooth, wrinkle-free skin, good vision, health and full of energy at eighty and even ninety years old. The Yuzurihara people grow and eat starchy root vegetables that stimulate the body to produce hyaluronic acid. One such plant is a small sweet potato called tamaji. Burdock or burdock Extract of burdock fruits reduces the signs of aging. This has been proven by research at the Beiersdorf AG Research Center in Hamburg, Germany. Burdock extract contains hyaluronic acid, and it was part of the topical formula. After four weeks, crow's feet wrinkles were "significantly reduced." Scientists have concluded that burdock effectively restores skin structure and reduces wrinkles. Warnings and Tips Smoking reduces the natural ability to produce hyaluronic acid, which leads to premature aging and wrinkles. Before increasing the amount of phyto-estrogens in your diet, you should consult your doctor.

Consuming hyaluronic acid with food does not affect the production of hyaluronic acid in the skin.

Any meat product (especially animal products) contains hyaluronic acid. When it enters the body, it is absorbed and then used for its intended purpose. But production and receipt are different processes. The body produces hyaluronic acid itself, but under the influence of certain factors. In its unchanged form, it does not reach further than the stomach. When you receive food containing hyaluronic acid, the latter is digested and absorbed, and then used by the body for its intended purpose. Therefore, it is impossible to say that hyaluronic acid supplied with food is the acid that is produced in the body and used by it.
The body has its own reserves of hyaluronic acid, and with the help of food (not without the participation of the famous ascorbic acid - vitamin C and the bioflavanoid rutin) you can preserve these reserves.
When talking about hyaluronic acid and its role in the body, it is better to talk not only about those products that contain it, but also about those that help preserve its reserves in the body.

Products that affect the supply and absorption of hyaluronic acid are, first of all, meat, which contains a lot of skin, tendons and joints.

And vitamin C and rutin contained in the white pulp of grapefruit peels, apricots, blackcurrants, blackberries, cherries, tomatoes, green tea, red pepper (paprika), cabbage, lettuce, grapes, raspberries help preserve its reserves.

The human body produces hyaluronic acid and hyaluronidase, which breaks down hyaluronic acid. With age, the production of hyaluronic acid decreases, therefore, at the first signs of skin aging and wrinkles, this problem is solved mainly from the outside - with injections, injections, etc.

Yes. But with age, the volume of hyaluronic acid produced by the body decreases. You can fill the deficiency with the help of creams, lotions and serums, subcutaneous injections, procedures using laser, ultrasound and microcurrent.

Hyaluronic acid makes the skin more elastic and firm, reduces wrinkles, gives additional volume to the lips and other parts of the body, and can even heal dermatitis.

German dermatologists were the first to identify Efficacy of cream-based novel formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment these magical properties of hyaluronan, a little later they conducted their research Efficacy and safety of a low-molecular weight hyaluronic Acid topical gel in the treatment of facial seborrheic dermatitis cosmetologists from the USA.

Where does the acid found in creams and injections come from?

At first, hyaluronic acid was obtained only from animal raw materials: cockscombs or animal umbilical cords. Over time, science came to the artificial production of hyaluronan in the laboratory. The second acids are purer in composition and more similar to human ones in properties.

They say that hyaluronic acid in creams is useless: its molecules are too large to penetrate into the deep layers of the skin. This is true?

Hyaluronan molecules are actually several times larger than the distance between skin cells. However, the acid does not have to penetrate too deeply to moisturize. It is enough to remain on the surface of the skin for some time to exert its water-retaining effect. In addition, for creams, lotions and serums, the molecules are specially broken down Hyaluronic acid - the key to retaining youthful moisture into small fractions.

Why do injections then?

Because their effect is more noticeable and lasts longer. The use of professional gels and creams with acid guarantees smooth skin within just 10–20 days. The effect of injections lasts on average 6–12 months (depending on the type of drug).

In the case of injections, hyaluronic acid acts as a filler. The substance seems to swell the skin from the inside, thereby smoothing out wrinkles and breasts or other areas of the body (but more often acid is still used for facial plastic surgery). This is why injections should only be done in specialized salons. experienced craftsman. If you inject too much of the drug, instead of a doll-like face and sensual lips, you risk getting cheek pillows and cushions instead of a mouth.

There are other dangers too. Sometimes drugs cause allergies, and during an injection you can introduce an infection into the body. Therefore, doctors do not recommend injections if you have an inflammatory disease, are pregnant or breastfeeding. After chemical or laser peeling It’s also better to postpone the procedure: the dermis needs time to recover.

Does hyaluronic acid cause acne?

The use of hyaluronan is included in complex therapy against. Acid normalizes work sebaceous glands, eliminates inflammation and helps regular renewal of skin cells.

Rashes that appear after injections due to improper care can be mistaken for acne. A puncture breaks the integrity of the skin and allows bacteria to easily enter the body. If you do not follow the rules of disinfection and care, small white pimples may appear at the puncture sites.

Is it addictive?

Only psychological. After hyaluronan stops stimulating hydration, the skin gradually returns to its original state. And the stimulation ends for completely natural reasons: the hyaluronic acid that has entered the body is included in the metabolic process and is gradually absorbed.

And the patient goes to another injection session or buys another jar of cream. But the condition of his skin did not worsen - it simply became the same as it was before the hyaluronan.

Does hyaluronic acid stop the aging process?

Hyaluronan deeply moisturizes the skin, restores its tone, smoothes out wrinkles. But skin aging is such a complex process that it cannot be reduced to dehydration alone. Using hyaluronic acid in creams or subcutaneous injections can visually rejuvenate you, but does not stop the natural progression of things.

Hyaluronic acid is not a cure for old age. This simply doesn't exist.